抗过敏天然产物研究进展

连晨蕾,丛慧,吴雅清,刘绪强,刘接卿

中国药学杂志 ›› 2017, Vol. 52 ›› Issue (12) : 997-1004.

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中国药学杂志 ›› 2017, Vol. 52 ›› Issue (12) : 997-1004. DOI: 10.11669/cpj.2017.12.001
综述

抗过敏天然产物研究进展

  • 连晨蕾1,丛慧1,吴雅清1,2,刘绪强1,2,刘接卿1,2*
作者信息 +

Research Progress of Anti-allergy Natural Products

  • LIAN Chen-lei1, CONG Hui1, WU Ya-qing1,2, LIU Xu-qiang1,2, LIU Jie-qing1,2*
Author information +
文章历史 +

摘要

利用Scifinder、ACS、CNKI及维普等数据库查阅近十年来国内外抗过敏天然产物研究相关报道,对不同结构类型的抗过敏天然产物进行总结。主要介绍了过敏性疾病的发病机制,抗过敏天然产物的活性部位、活性单体、来源及作用机制等方面。天然产物抗过敏作用靶点多,毒副作用小,但目前该方向的研究尚有不足之处,在此基础上提出抗过敏中药或天然药物研究的几个思路,为进一步研究抗过敏天然药物提供参考。

Abstract

Based on overseas and domestic data bank mainly as Scifinder, ACS publication, CNKI, and CQVIP. The relationships between the types of natural products and their anti-allergic activities have been summarized. The advances of anti-allergic natural products over the past ten years have been reviewed. The pathogenesis of allergic diseases and the diversity of anti-allergy components and natural products were summarized, together with their origins and mechanisms of anti-allergy activities. Many natural products show multiple anti-allergy targets and few side effects, while the research is still far from enough. Several suggestions were proposed for further research on anti-allergy natural medicines on the basis of our review.

关键词

抗过敏 / 天然产物 / 化学结构 / 作用机制

Key words

anti-allergy / natural product / chemical structure / mechanism

引用本文

导出引用
连晨蕾,丛慧,吴雅清,刘绪强,刘接卿. 抗过敏天然产物研究进展[J]. 中国药学杂志, 2017, 52(12): 997-1004 https://doi.org/10.11669/cpj.2017.12.001
LIAN Chen-lei, CONG Hui, WU Ya-qing, LIU Xu-qiang, LIU Jie-qing. Research Progress of Anti-allergy Natural Products[J]. Chinese Pharmaceutical Journal, 2017, 52(12): 997-1004 https://doi.org/10.11669/cpj.2017.12.001
中图分类号: R284   

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基金

福建省高校青年自然基金重点项目(Z1625138);华侨大学中青年教师科研提升资助计划(600005-Z15J0025);华侨大学科研基金资助项目(600005-Z15Y0015);华侨大学研究生科研创新能力培育计划资助项目
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